A new model system for investigation of ionic channels in filamentous fungi: evidence for existence of two K+-permeable ionic channels in Phycomyces blakesleeanus

Ann N Y Acad Sci. 2005 Jun:1048:491-5. doi: 10.1196/annals.1342.075.

Abstract

A technique was developed to obtain viable cytoplasmic droplets, enabling the formation of a gigaohm seal. Such cytoplasmic droplets can be used for characterization of plasma membrane ion channels from filamentous fungi by patch-clamp technique. Two K(+) ionic channels are characterized with a conductance of 43 pS and 74 pS.

MeSH terms

  • Cell Membrane Permeability / physiology*
  • Cytoplasm / chemistry
  • Cytoplasm / ultrastructure
  • Electrophysiology / instrumentation
  • Electrophysiology / methods*
  • Fungi / growth & development*
  • Fungi / ultrastructure
  • Ion Channels / physiology*
  • Membrane Potentials / physiology
  • Models, Biological
  • Patch-Clamp Techniques
  • Phycomyces / physiology*
  • Potassium Channels / physiology

Substances

  • Ion Channels
  • Potassium Channels