Five single nucleotide polymorphisms (SNP) of the chicken insulin-like factor binding protein 2 (IGFBP2) gene were selected to genotype a F2 designed population with restriction fragment length polymorphisms and single stranded-conformation polymorphisms. The associations of the SNP and their haplotypes with chicken growth and carcass traits were analyzed. Results showed that the difference induced by the haplotypes derived from the 5 SNP was more significant than that by the single SNP in the genotype-phenotype association analysis. The haplotypes were associated with BW at hatch and at 21, 28, 42, 49, 56, and 90 d of age, as well as eviscerated weight with giblets (EWG), eviscerated weight (EW), and weights of heart, liver, and gizzard (HLGW) (P < or = 0.01). The haplotypes were also related to BW at 7, 14, and 35 d of age, breast depth, carcass weight, and breast muscle weight (P < or = 0.05). Significant and suggestive dominant effects of H1H5 diplotype were detected for BW at 7, 14, 21, 28, and 90 d of age, as well as breast depth, carcass weight, eviscerated weight with giblets, eviscerated weight, breast muscle weight, leg muscle weight, and weights of heart, liver, and gizzard. It was concluded that H1H5 was the most advantageous diplotype, and H4H10 was the negative diplotype for growth and carcass traits.