What is the risk of nocturnal supine enteral nutrition?

Clin Nutr. 2005 Dec;24(6):1014-8. doi: 10.1016/j.clnu.2005.08.001. Epub 2005 Sep 13.

Abstract

One complication of enteral nutrition (EN) is gastro-esophageal reflux disease. Semi-recumbent position is advised because posture influence reflux in critically ill patients. No data is available in stable patients.

Aim: To study influence of position on reflux during nocturnal nutrition by percutaneous endoscopic gastrostomy in stable patients.

Methods: Prospective cross-over study. Reflux was measured by 48 h-pH-metry, in supine and semi-recumbent position. The end point was % time spent under pH 4. For analysis, 2 subgroups were identified (refluxers and non-refluxers). A total of 16 patients (65 year+/-13) were included, most had neurological diseases.

Results: There was no increase of reflux probability in any position in all patients (% time spent under pH 4: supine vs. semi-recumbent: 4.4+/-7.7 vs. 3.5+/-7.0 NS). In non-refluxers, supine position did not increase % time under pH 4 (0.1+/-0.12 vs. 0.3+/-0.6, NS), and did not modify other parameters (number of reflux 0 +/-0.9 vs. 7 +/-19 NS, duration of the longest reflux (min) 1.1+/-1.7 vs. 1+/-1.7 NS). In refluxers, supine position did not worsen pre-existent reflux (% time under pH 4: 11.7+/-8.7 vs. 8.9+/-9.7 NS, number of reflux 119+/-88 vs. 91+/-89 NS, duration of the longest reflux (min) 19+/-19 vs. 24+/-21 NS).

Conclusion: Our data suggest that position does not influence reflux in stable patients with EN.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Cross-Over Studies
  • Enteral Nutrition / adverse effects*
  • Gastroesophageal Reflux / etiology
  • Gastroesophageal Reflux / prevention & control*
  • Gastrostomy
  • Humans
  • Hydrogen-Ion Concentration
  • Middle Aged
  • Monitoring, Physiologic
  • Pilot Projects
  • Prospective Studies
  • Risk Factors
  • Supine Position* / physiology