Long-term effectiveness of total arch replacement for type A aortic dissection

Ann Thorac Surg. 2005 Oct;80(4):1297-302. doi: 10.1016/j.athoracsur.2005.04.004.

Abstract

Background: With recent improvements in cerebral protection during aortic arch repair, total aortic arch replacement has become an accepted surgical method for acute type A aortic dissection involving the aortic arch. Our surgical strategy is to perform total arch replacement with a branched graft using antegrade selective cerebral perfusion for the patients with type A aortic dissection involving the aortic arch. The objective of this study is to evaluate the effectiveness of this strategy on late outcome.

Methods: From October 1988 to April 2003, 46 patients underwent total arch replacement for acute type A dissection involving the aortic arch. Operations were performed with hypothermic cardiopulmonary bypass, antegrade selective cerebral perfusion during the arch repair, and open distal anastomosis.

Results: Hospital mortality was 6.5% (3 patients), and permanent neurologic dysfunction was observed in 1 patient. During the follow-up period (mean, 5.4 years; range, 13 months to 15.6 years), 2 patients died, but the causes were not related to the aorta or aortic valve. Survival rates at 5 and 10 years postoperatively were 89.6% +/- 5.2% and 82.7% +/- 8.2%, respectively. Of the 41 survivors, 3 patients underwent successful reoperation for the distal thoracic aorta. Freedom from reoperation was 93.6% +/- 4.6% and 88.7% +/- 6.5% at 5 and 10 years, respectively. The residual false lumen in the thoracic aorta was frequently thrombosed (76.2%).

Conclusions: Total arch replacement for acute type A dissection may decrease the risk of late complications related to the false lumen and lead to excellent long-term survival.

MeSH terms

  • Acute Kidney Injury / etiology
  • Adult
  • Aged
  • Anastomosis, Surgical
  • Aorta, Thoracic / surgery*
  • Aortic Aneurysm / classification
  • Aortic Aneurysm / surgery*
  • Aortic Dissection / classification
  • Aortic Dissection / surgery*
  • Female
  • Follow-Up Studies
  • Humans
  • Longitudinal Studies
  • Male
  • Middle Aged
  • Nervous System Diseases / etiology
  • Outcome and Process Assessment, Health Care
  • Reoperation / statistics & numerical data
  • Respiratory Insufficiency / etiology
  • Risk Factors
  • Survival Analysis
  • Thrombosis / etiology
  • Treatment Outcome
  • Vascular Patency
  • Vascular Surgical Procedures / adverse effects
  • Vascular Surgical Procedures / mortality
  • Vascular Surgical Procedures / statistics & numerical data