HLA-A*2626, a new allele identified through external proficiency-testing exercise

Tissue Antigens. 2005 Oct;66(4):325-6. doi: 10.1111/j.1399-0039.2005.00468.x.

Abstract

A new allele, officially named HLA-A*2626, has been detected in a blood sample belonging to a Caucasian subject human leucocyte antigen typed for Lombardy Region external proficiency-testing exercise. The DNA sequences of exons 2, 3 and 4 of this new allele are identical to those of HLA-A*2601 except at codon 259 of exon 4 (CCT-->CTT). This variation modifies the encoded protein from proline to leucine.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles*
  • Amino Acid Substitution / genetics*
  • Amino Acid Substitution / immunology
  • Base Sequence
  • Exons / genetics*
  • Exons / immunology
  • Female
  • HLA-A Antigens / genetics*
  • HLA-A Antigens / immunology
  • Humans
  • Male
  • Molecular Sequence Data
  • Point Mutation / genetics*
  • Point Mutation / immunology

Substances

  • HLA-A Antigens
  • HLA-A*26:26 antigen

Associated data

  • GENBANK/AJ890835