Clinical outcome in patients with high-grade internal carotid artery stenosis after irradiation

Neurology. 2005 Sep 27;65(6):959-61. doi: 10.1212/01.wnl.0000176033.64896.c6.

Abstract

The authors followed up 41 consecutive patients (21 symptomatic) with internal carotid artery stenosis > or =70% and previous neck irradiation. After 28 months, 15 patients (36.6%) had died, five (12.2%) had had an ischemic stroke, and 15 (36.6%) had a new malignancy. Having a new malignancy was the only independent predictor of death. The major risk for patients with ICA stenosis > or =70% and previous neck irradiation is malignancy, not stroke.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Angioplasty / statistics & numerical data
  • Carotid Stenosis / mortality*
  • Causality
  • Comorbidity
  • Endarterectomy, Carotid / statistics & numerical data
  • Female
  • Follow-Up Studies
  • France / epidemiology
  • Head and Neck Neoplasms / mortality*
  • Head and Neck Neoplasms / radiotherapy
  • Humans
  • Interviews as Topic
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local / mortality*
  • Neoplasms, Second Primary / mortality*
  • Prospective Studies
  • Radiotherapy / adverse effects*
  • Risk Factors
  • Stroke / mortality*
  • Survival Analysis
  • Treatment Outcome