Association between BDNF Val66Met polymorphism and age at onset in Huntington disease

Neurology. 2005 Sep 27;65(6):964-5. doi: 10.1212/01.wnl.0000175977.57661.b1.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Age of Onset
  • Amino Acid Substitution / genetics*
  • Brain-Derived Neurotrophic Factor / chemistry
  • Brain-Derived Neurotrophic Factor / genetics*
  • Brain-Derived Neurotrophic Factor / metabolism
  • DNA Mutational Analysis
  • Female
  • Gene Frequency
  • Genetic Predisposition to Disease / genetics*
  • Genetic Testing
  • Genotype
  • Humans
  • Huntingtin Protein
  • Huntington Disease / epidemiology
  • Huntington Disease / genetics*
  • Huntington Disease / metabolism
  • Male
  • Methionine / genetics
  • Middle Aged
  • Mutation / genetics*
  • Nerve Tissue Proteins / genetics
  • Nerve Tissue Proteins / metabolism
  • Nuclear Proteins / genetics
  • Nuclear Proteins / metabolism
  • Polymorphism, Genetic / genetics*
  • Trinucleotide Repeat Expansion / genetics
  • Valine / genetics

Substances

  • Brain-Derived Neurotrophic Factor
  • HTT protein, human
  • Huntingtin Protein
  • Nerve Tissue Proteins
  • Nuclear Proteins
  • Methionine
  • Valine