Fatal HHV-6 associated encephalitis in an HIV-1 infected patient treated with cidofovir

J Infect. 2006 Apr;52(4):237-42. doi: 10.1016/j.jinf.2005.07.006. Epub 2005 Sep 26.

Abstract

We describe the case of a patient infected with HIV and a concomitant HHV-6 encephalitis. The patient experienced virological failure following cidofovir treatment. RT-PCR was used both for early diagnosis and follow-up.

Publication types

  • Case Reports

MeSH terms

  • Antiviral Agents / adverse effects
  • Antiviral Agents / therapeutic use*
  • Biopsy
  • Brain / pathology
  • Brain / virology
  • Cidofovir
  • Cytosine / adverse effects
  • Cytosine / analogs & derivatives*
  • Cytosine / therapeutic use
  • Encephalitis, Viral / complications
  • Encephalitis, Viral / diagnosis
  • Encephalitis, Viral / drug therapy*
  • Fatal Outcome
  • Female
  • HIV Infections / complications*
  • HIV Infections / drug therapy
  • HIV-1
  • Herpesvirus 6, Human / genetics
  • Herpesvirus 6, Human / isolation & purification*
  • Herpesvirus 6, Human / pathogenicity
  • Humans
  • Magnetic Resonance Imaging
  • Middle Aged
  • Organophosphonates / adverse effects
  • Organophosphonates / therapeutic use*
  • Polymerase Chain Reaction
  • Roseolovirus Infections / complications
  • Roseolovirus Infections / diagnosis
  • Roseolovirus Infections / drug therapy*
  • Viral Load

Substances

  • Antiviral Agents
  • Organophosphonates
  • Cytosine
  • Cidofovir