Lewis acid-promoted reactions of zirconacyclopentadienes with isocyanates. A one-pot three-component synthesis of multiply-substituted iminocyclopentadienes from one isocyanate and two alkynes

Chem Commun (Camb). 2005 Oct 14:(38):4848-50. doi: 10.1039/b509142j. Epub 2005 Sep 5.

Abstract

Multiply-substituted iminocyclopentadienes were formed from Lewis acid-promoted reactions of zirconacyclopentadienes and isocyanates via a one-pot three-component coupling process; the C=O double bond of the RN=C=O moiety in the isocyanate was cleaved, and the isocyanates behaved formally as a one-carbon unit with Lewis acid-dependent and substituent-dependent reactions being realized.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkynes / chemistry*
  • Cyclopentanes / chemical synthesis*
  • Cyclopentanes / chemistry*
  • Isocyanates / chemistry*
  • Molecular Structure
  • Organometallic Compounds / chemistry*
  • Zirconium / chemistry*

Substances

  • Alkynes
  • Cyclopentanes
  • Isocyanates
  • Organometallic Compounds
  • Zirconium