Antithrombotic therapy for stroke in young adults

J Thromb Thrombolysis. 2005 Oct;20(2):127-32. doi: 10.1007/s11239-005-3206-4.

Abstract

Stroke in young adults is a markedly heterogeneous disease, and remains an understudied phenomenon. While advances are being made in our understanding of the pathophysiology of its underlying conditions, treatment concerns are controversial, and clinical trials are sorely lacking. This review presents an overview of some of the relevant management issues in hypercoagulable states, migraine, patent foramen ovale, vascular dissection and venous sinus thrombosis.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Anticoagulants / therapeutic use
  • Blood Coagulation Factors / genetics
  • Carotid Artery, Internal, Dissection / complications
  • Clinical Trials as Topic
  • Fibrinolytic Agents / therapeutic use*
  • Heart Septal Defects, Atrial / complications
  • Humans
  • Migraine Disorders / complications
  • Platelet Aggregation Inhibitors / therapeutic use
  • Risk Factors
  • Secondary Prevention
  • Sinus Thrombosis, Intracranial / complications
  • Stroke / etiology
  • Stroke / prevention & control*
  • Thrombophilia / complications
  • Thrombophilia / genetics
  • Vertebral Artery Dissection / complications

Substances

  • Anticoagulants
  • Blood Coagulation Factors
  • Fibrinolytic Agents
  • Platelet Aggregation Inhibitors