Abstract
We evaluated the presence of human herpesvirus 8 (HHV-8) infection among groups of Amerindians in French Guiana. The overall prevalence of antibodies against lytic HHV-8 antigens was 23.0% (180/781), increasing from 18.4% in children <6 years old to approximately 30% in older persons (>45 years). Seroprevalence was higher in Amerindians living in remote localities than it was in those living in the coastal region. Analysis of a 725-base pair fragment of the K1 gene amplified from DNA from a Wayampi Amerindian showed that the virus belonged to molecular subtype E, which has hitherto been found in only a few Amerindians in Brazil and Ecuador.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Adult
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Aged
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Aged, 80 and over
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Antibodies, Viral / blood
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Basic-Leucine Zipper Transcription Factors / immunology
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Child
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Child, Preschool
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DNA, Viral / genetics
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Endemic Diseases*
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French Guiana / epidemiology
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Genes, Viral
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Herpesviridae Infections / blood
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Herpesviridae Infections / epidemiology*
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Herpesviridae Infections / ethnology*
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Herpesviridae Infections / virology
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Herpesvirus 8, Human / classification*
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Herpesvirus 8, Human / genetics
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Herpesvirus 8, Human / isolation & purification*
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Humans
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Indians, North American*
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Infant
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Middle Aged
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Prevalence
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Repressor Proteins / immunology
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Rural Population
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Seroepidemiologic Studies
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Viral Proteins / genetics
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Viral Proteins / immunology
Substances
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Antibodies, Viral
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Basic-Leucine Zipper Transcription Factors
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DNA, Viral
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K1 protein, Human herpesvirus 8
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K8 protein, Human herpesvirus 8
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Repressor Proteins
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Viral Proteins