Use of stored serum from Uganda for development and evaluation of a human immunodeficiency virus type 1 testing algorithm involving multiple rapid immunoassays

J Clin Microbiol. 2005 Oct;43(10):5312-5. doi: 10.1128/JCM.43.10.5312-5315.2005.

Abstract

We report the development and evaluation of a human immunodeficiency virus type 1 testing algorithm consisting of three rapid antibody detection tests. Stored serum samples from Uganda were utilized with a final algorithm sensitivity of 100% and a specificity of 98.9% (95% confidence interval, 98.6% to 99.3%).

Publication types

  • Evaluation Study
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • AIDS Serodiagnosis*
  • Algorithms*
  • Confidence Intervals
  • HIV Antibodies / blood*
  • HIV Infections / diagnosis*
  • HIV Infections / virology
  • HIV-1 / immunology*
  • Humans
  • Immunoassay / methods
  • Sensitivity and Specificity
  • Serum
  • Specimen Handling / methods*
  • Time Factors
  • Uganda

Substances

  • HIV Antibodies