Objective: To study the effect of compound nonoxinol on the inhibition of bacteria in vitro.
Methods: The minimal bactericidal concentration (MBC) and minimal bactericidal time (MBT) of nonoxinol providine iodine and compound nonoxinol, composed of nonoxinol and providine iodine were determined by inhibiting C. albicans and N. gonorrhoeae.
Results: Nonoxinol alone showed no inhibiting effects on bacteria. The MBT was 2 minutes for both compound nonoxinol and providine iodine, but the MBC of providine iodine was higher than that of compound nonoxinol.
Conclusion: Compound nonoxinol works better in inhibiting bacteria than either nonoxinoother or providine iodine used alone.