Electrostatic potentials of E.coli genome DNA

S G Kamzolova; A A Sorokin; T D Dzhelyadin; P M Beskaravainy; A A Osypov

Electrostatic potentials of E.coli genome DNA

J Biomol Struct Dyn. 2005 Dec;23(3):341-5.

Authors

S G Kamzolova¹, A A Sorokin, T D Dzhelyadin, P M Beskaravainy, A A Osypov

Affiliation

¹ Institute of Cell Biophysics of RAS, Pushchino, Moscow region 142290, Russia.

PMID: 16218758

Abstract

Distribution of electrostatic potential of the complete sequence of E. coli genome was calculated. Comparative analysis of electrostatic patterns for 359 promoter and nonpromoter nucleotide sequences was carried out. It is found that nonpromoter regions are characterized by more homogeneous distribution of electrostatic potential with no common specific elements. Electrostatic patterns of promoter DNAs can be specified due to the presence of some distinctive motifs which may be involved as promoter signal elements in RNA-polymerase-promoter recognition.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Base Sequence
DNA / chemistry*
Escherichia coli / genetics*
Genome, Bacterial*
Molecular Sequence Data
Operon
Promoter Regions, Genetic*
Static Electricity

Substances

DNA