A case of acute humoral rejection in liver transplantation: successful treatment with plasmapheresis and mycophenolate mofetil

Transpl Int. 2005 Nov;18(11):1298-301. doi: 10.1111/j.1432-2277.2005.00200.x.

Abstract

We present a case of a 23-year-old female who underwent orthotopic liver transplantation (OLTx) for biliary atresia, 22 years after a failed Kasai operation. Unusually, her postoperative course was complicated by severe acute humoral rejection. In this case report, we discuss her management as well as the role of plasmapheresis in treating allograft dysfunction secondary to acute humoral rejection in liver transplant patients.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adult
  • Antibody Formation
  • Biliary Atresia / surgery
  • Combined Modality Therapy
  • Female
  • Graft Rejection / drug therapy*
  • Graft Rejection / immunology
  • Graft Rejection / pathology
  • Humans
  • Immunosuppressive Agents / administration & dosage*
  • Liver Transplantation*
  • Mycophenolic Acid / administration & dosage
  • Mycophenolic Acid / analogs & derivatives*
  • Plasmapheresis*

Substances

  • Immunosuppressive Agents
  • Mycophenolic Acid