Abstract
Actin participates in many important biological processes. Currently, intensive investigation is being carried out in a number of laboratories concerning the function of actin in these processes and the molecular basis of its functions. We present a glimpse into four of these areas: actin-like proteins in bacterial cells, actin in the eukaryotic nucleus, the conformational plasticity of the actin filament, and finally, Arp2/3-dependent regulation of actin filament branching and creation of new filament barbed ends.
IUBMB Life, 57: 683-687, 2005.
Publication types
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Research Support, N.I.H., Extramural
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Review
MeSH terms
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Actin-Related Protein 2-3 Complex / chemistry
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Actins / chemistry
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Actins / metabolism
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Actins / physiology*
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Animals
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Cell Nucleus / physiology
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Escherichia coli Proteins / metabolism
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Humans
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Models, Molecular
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Protein Conformation
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Saccharomyces cerevisiae Proteins / physiology
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Wiskott-Aldrich Syndrome Protein / physiology
Substances
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Actin-Related Protein 2-3 Complex
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Actins
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Escherichia coli Proteins
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LAS17 protein, S cerevisiae
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ParM protein, E coli
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Saccharomyces cerevisiae Proteins
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Wiskott-Aldrich Syndrome Protein
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MreB protein, E coli