Chemical composition and pharmacological activity of essential oil of Canarium schweinfurthii

Fitoterapia. 2005 Dec;76(7-8):700-3. doi: 10.1016/j.fitote.2005.06.004. Epub 2005 Oct 18.

Abstract

The essential oil obtained by hydrodistillation of the resin of Canarium schweinfurthii growing in Central African Republic, was analysed by GC and GC/MS and its analgesic and antiinflammatory effects were studied. The major constituents of the essential oil were octylacetate (60%) and nerolidol (14%). At the doses of 1, 2 and 3 ml/kg i.p. essential oil shows a significant analgesic effect using acetic acid-induced writhing and hot plate methods. However, its was unable to reduce inflammatory process in cotton pellet induced granuloma method.

MeSH terms

  • Analgesics / pharmacology*
  • Animals
  • Anti-Inflammatory Agents / pharmacology*
  • Burseraceae / chemistry*
  • Mice
  • Oils, Volatile / chemistry*
  • Oils, Volatile / pharmacology*

Substances

  • Analgesics
  • Anti-Inflammatory Agents
  • Oils, Volatile