Recognition of septanose carbohydrates by concanavalin A

Org Biomol Chem. 2005 Nov 7;3(21):3869-72. doi: 10.1039/b509243d. Epub 2005 Sep 26.

Abstract

The ability of the jack bean lectin concanavalin A (ConA) to bind seven membered ring (septanose) monosaccharides has been investigated by isothermal titration calorimetry (ITC) and saturation transfer difference (STD) NMR spectroscopy.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Binding Sites
  • Calorimetry
  • Concanavalin A / chemistry*
  • Concanavalin A / metabolism
  • Heptoses / chemistry*
  • Heptoses / metabolism
  • Magnetic Resonance Spectroscopy
  • Protein Binding
  • Titrimetry

Substances

  • Heptoses
  • Concanavalin A