Successful thrombolytic therapy for prosthetic mitral valve thrombosis with hemodynamic obstruction: case report and review of the literature

J Heart Valve Dis. 2005 Sep;14(5):687-92.

Abstract

Prosthetic valve thrombosis (PVT) is a serious complication of mechanical valves. The use of thrombolytic therapy to relieve thrombotic prosthetic valve obstruction is accepted for right-sided valves, but its role in left-sided valves and hemodynamically stable patients awaits clarification. The case is presented of a patient in whom prosthetic heart valve thrombosis was treated successfully with streptokinase under transesophageal echocardiographic guidance.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Echocardiography
  • Echocardiography, Transesophageal
  • Female
  • Fibrinolytic Agents / therapeutic use*
  • Heart Valve Prosthesis*
  • Humans
  • Middle Aged
  • Mitral Valve Stenosis / diagnostic imaging
  • Mitral Valve Stenosis / physiopathology
  • Mitral Valve Stenosis / therapy*
  • Prosthesis Failure
  • Rheumatic Heart Disease / diagnostic imaging
  • Rheumatic Heart Disease / physiopathology
  • Rheumatic Heart Disease / therapy
  • Streptokinase / therapeutic use*
  • Thrombolytic Therapy*

Substances

  • Fibrinolytic Agents
  • Streptokinase