Abstract
Investigation of the stem bark of the unique Amazonian herbal plant Potalia amara yielded two new phenolic glycosides, potalioside A (1) and B (2), along with di-O-methylcrenatin (3), 2,6-dimethoxy-4-hydroxyphenol 1-glucoside and sweroside. The structures of potalioside A and B were established by interpretation of spectral data as 4-hydroxymethyl-2,6-dimethoxyphenyl 1-O-beta-D-glucopyranosyl(1-->6)-beta-D-glucopyranoside and 4-hydroxymethyl-2,6-dimethoxyphenyl 1-O-beta- D-xylopyranosyl(1-->6)- beta-D-glucopyranoside, respectively.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Anti-Bacterial Agents / administration & dosage
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Anti-Bacterial Agents / pharmacology
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Anti-Bacterial Agents / therapeutic use
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Bacteria / drug effects
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Brazil
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Candida albicans / drug effects
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Gentianaceae*
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Glycosides / administration & dosage
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Glycosides / pharmacology
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Glycosides / therapeutic use
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Humans
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Medicine, Traditional
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Microbial Sensitivity Tests
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Phenols / administration & dosage
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Phenols / pharmacology
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Phenols / therapeutic use
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Phytotherapy*
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Plant Bark
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Plant Extracts / administration & dosage
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Plant Extracts / pharmacology*
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Plant Extracts / therapeutic use
Substances
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Anti-Bacterial Agents
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Glycosides
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Phenols
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Plant Extracts