Brief report: severe symptoms of hyperhistaminemia after the treatment of acute promyelocytic leukemia with tretinoin (all-trans-retinoic acid)

N Engl J Med. 1992 Aug 6;327(6):385-7. doi: 10.1056/NEJM199208063270604.
No abstract available

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antineoplastic Agents / administration & dosage
  • Antineoplastic Agents / adverse effects*
  • Antineoplastic Agents / pharmacology
  • Basophils
  • Bone Marrow / pathology
  • Cell Differentiation / drug effects
  • Histamine / blood*
  • Humans
  • Leukemia, Promyelocytic, Acute / drug therapy*
  • Leukemia, Promyelocytic, Acute / pathology
  • Leukocyte Count
  • Leukocytosis / chemically induced
  • Male
  • Peptic Ulcer / chemically induced
  • Tretinoin / administration & dosage
  • Tretinoin / adverse effects*
  • Tretinoin / pharmacology

Substances

  • Antineoplastic Agents
  • Tretinoin
  • Histamine