Dual function of focal adhesion kinase in regulating integrin-induced MMP-2 and MMP-9 release by human T lymphoid cells

FASEB J. 2005 Nov;19(13):1875-7. doi: 10.1096/fj.04-3574fje.
No abstract available

MeSH terms

  • Binding Sites
  • Cell Adhesion
  • Cell Line
  • DNA, Complementary / metabolism
  • Fibronectins / chemistry
  • Fibronectins / metabolism
  • Focal Adhesion Protein-Tyrosine Kinases / metabolism
  • Focal Adhesion Protein-Tyrosine Kinases / physiology*
  • Gelatinases / metabolism
  • Gene Expression Regulation, Enzymologic*
  • Humans
  • Integrins / metabolism*
  • Jurkat Cells
  • Matrix Metalloproteinase 2 / biosynthesis*
  • Matrix Metalloproteinase 9 / biosynthesis*
  • Models, Biological
  • Mutation
  • Phosphorylation
  • Protein Structure, Tertiary
  • RNA Processing, Post-Transcriptional
  • Reverse Transcriptase Polymerase Chain Reaction
  • Signal Transduction
  • T-Lymphocytes / enzymology
  • T-Lymphocytes / metabolism*
  • Time Factors
  • Transfection
  • src-Family Kinases / metabolism

Substances

  • DNA, Complementary
  • Fibronectins
  • Integrins
  • Focal Adhesion Protein-Tyrosine Kinases
  • src-Family Kinases
  • Gelatinases
  • Matrix Metalloproteinase 2
  • Matrix Metalloproteinase 9