Infliximab in a child with therapy-resistant systemic vasculitis

Clin Rheumatol. 2006 Sep;25(5):769-71. doi: 10.1007/s10067-005-0071-7. Epub 2005 Nov 3.

Abstract

Treatment of systemic vasculitides is usually based on the use of corticosteroids and other immunosuppressive drugs. We describe a 10-year-old girl with systemic vasculitis resistant to immunosuppressive treatment who had a rapid and impressive response to treatment with infliximab.

Publication types

  • Case Reports

MeSH terms

  • Antibodies, Monoclonal / therapeutic use*
  • Antirheumatic Agents / therapeutic use*
  • Child
  • Female
  • Humans
  • Infliximab
  • Polyarteritis Nodosa / drug therapy*
  • Polyarteritis Nodosa / pathology
  • Remission Induction
  • Treatment Outcome
  • Tumor Necrosis Factor-alpha / antagonists & inhibitors*

Substances

  • Antibodies, Monoclonal
  • Antirheumatic Agents
  • Tumor Necrosis Factor-alpha
  • Infliximab