Abstract
A new phenolic glucoside (1), pursargentoside, was isolated from the leaves of Prunus serrulata var. spontanea, along with three other known compounds, orobol 7-omicron-glucoside (2), 1beta, 2alpha, 3alpha, 24-tetrahydroxy-urs-12-en-28-oic acid (3), and chlorogenic acid (4). The structure of pursargentoside (1) was identified by spectroscopic data analysis including 1D and 2D NMR spectroscopy, as 2-omicron-beta-(6'-benzoyl)-glucopyranosyl omicron-(Z)-coumaric acid. Compounds 1, 2, and 4 exhibited ONOO scavenging activity, whereas compound 3 was determined to be virtually inactive.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Free Radical Scavengers / chemistry
-
Free Radical Scavengers / isolation & purification
-
Free Radical Scavengers / pharmacology
-
Glucosides / chemistry
-
Glucosides / isolation & purification*
-
Glucosides / pharmacology
-
Magnetic Resonance Spectroscopy
-
Oxidation-Reduction / drug effects
-
Peroxynitrous Acid / chemistry*
-
Phenol / chemistry
-
Phenol / isolation & purification
-
Phenol / pharmacology
-
Plant Extracts / chemistry
-
Plant Extracts / isolation & purification
-
Plant Extracts / pharmacology
-
Plant Leaves / chemistry
-
Prunus / chemistry*
Substances
-
Free Radical Scavengers
-
Glucosides
-
Plant Extracts
-
Peroxynitrous Acid
-
Phenol