Fine-tuning insulin and nitric oxide signalling by turning up the AMPs: new insights into AMP-activated protein kinase signalling

Diabetologia. 2005 Dec;48(12):2451-3. doi: 10.1007/s00125-005-0032-3. Epub 2005 Nov 11.

Authors

Y C Long¹, J R Zierath

Affiliation

¹ Section for Integrative Physiology, Department of Molecular Medicine and Surgery, Karolinska Institute, von Eulers väg 4, II, SE-171 77, Stockholm, Sweden.

PMID: 16283241
DOI: 10.1007/s00125-005-0032-3

No abstract available

Publication types

Comment

MeSH terms

AMP-Activated Protein Kinases
Adenosine Monophosphate / physiology*
Aminoimidazole Carboxamide / analogs & derivatives
Aminoimidazole Carboxamide / pharmacology
Animals
Diabetes Mellitus, Type 2 / metabolism
Enzyme Activation
Glucose / metabolism
Insulin / pharmacology
Insulin / physiology*
Male
Multienzyme Complexes / physiology*
Myocardium / enzymology
Nitric Oxide / physiology*
Nitric Oxide Donors / pharmacology
Nitroprusside / pharmacology
Phosphatidylinositol 3-Kinases / physiology
Phosphorylation
Protein Serine-Threonine Kinases / physiology*
Proto-Oncogene Proteins c-akt / physiology
Rats
Rats, Sprague-Dawley
Ribonucleotides / pharmacology
Signal Transduction / physiology*

Substances

Insulin
Multienzyme Complexes
Nitric Oxide Donors
Ribonucleotides
Nitroprusside
Nitric Oxide
Aminoimidazole Carboxamide
Adenosine Monophosphate
Protein Serine-Threonine Kinases
Proto-Oncogene Proteins c-akt
AMP-Activated Protein Kinases
AICA ribonucleotide
Glucose