Neurocytoma of the VIIIth cranial nerve: case report

Neurosurgery. 2005 Nov;57(5):E1065; discussion E1065. doi: 10.1227/01.neu.0000179981.62074.b1.

Abstract

Objective and importance: Neurocytomas are uncommon tumors of the CNS. To date, none have been described in association with a cranial nerve. We described the clinicopathological features of an example arising in the cochlear-vestibular portion of the VIIIth nerve with extension into the cerebellopontine angle.

Clinical presentation: The patient, a 42-year-old female, presented approximately 6 months ago with several episodes of worsening dizziness. On magnetic resonance imaging studies, a 2-cm enhancing lesion occupying the left internal auditory canal and protruding into the cerebellopontine angle cistern was detected with signal characteristics suggestive of vestibular neuroma.

Intervention: At surgery, the tumor was seen to originate from the cochlear-vestibular nerve bundle lying within the internal auditory canal, extended laterally to the level of the fundus and 4 mm medially into the cerebellopontine angle. No dural attachment was noted. With use of sharp dissection and bipolar cautery, portions of the tumor within the auditory canal were debulked.

Conclusion: A unique example of a neurocytoma in association with a cranial nerve is documented. Possible explanations for the occurrence are explored. The topography of neurocytomas continues to expand.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cranial Nerve Neoplasms / surgery*
  • Female
  • Follow-Up Studies
  • Humans
  • Immunohistochemistry / methods
  • Magnetic Resonance Imaging / methods
  • Neurocytoma / surgery*
  • Neurosurgery
  • Synaptophysin / metabolism
  • Tomography, X-Ray Computed
  • Vestibulocochlear Nerve / pathology*
  • Vestibulocochlear Nerve / surgery

Substances

  • Synaptophysin