Salivary gland Basal cell adenomas--immunohistochemical evaluation of four cases and review of the literature

Rom J Morphol Embryol. 2005;46(1):29-40.

Abstract

Objective: Evaluate the antigen profile of cellular population from basal cell adenomas.

Material and methods: Histopathological and immunohistochemical evaluation of four-salivary gland basal cell adenomas; the pathological samples were provided by the Oral Maxilla Facial Surgery Department of the Clinical County Hospital from Craiova.

Results: All basal cell adenoma exhibit differentiation toward 3 cell phenotypes: ductal luminal, basal and myoepithelial.

Conclusions: The antigen profile of these tumors closely regard with other variants of salivary gland adenomas, such as pleomorphic adenoma and myoepithelioma. So, we can conclude that these tumors had a common origin, most probably from intercalated ducts and the proportion of those 3 cellular types, their cytoarchitectural arrangements and the quantity of extracellular matrix production can do the differentiation between them.

Publication types

  • Review

MeSH terms

  • Adenoma / pathology*
  • Female
  • Humans
  • Immunohistochemistry / methods
  • Male
  • Middle Aged
  • Proliferating Cell Nuclear Antigen / analysis
  • Salivary Gland Neoplasms / pathology*

Substances

  • Proliferating Cell Nuclear Antigen