Abstract
Microcytosis is a characteristic laboratory feature for both iron deficiency anemia and thalassemia. It is also infrequently seen in "anemia of chronic disease" that accompanies a spectrum of chronic conditions including rheumatoid arthritis, polymyalgia rheumatica, diabetes mellitus, connective tissue disease, and protracted infection. In addition, there is a well established but pathogenetically obscure association of microcytosis with Hodgkin's lymphoma, Castleman's disease, and renal cell carcinoma. In the current study, we show that microcytosis is a frequent laboratory feature in agnogenic myeloid metaplasia and investigate its clinical relevance in the particular setting.
MeSH terms
-
Adolescent
-
Adult
-
Anemia, Iron-Deficiency / complications
-
Anemia, Iron-Deficiency / mortality
-
Anemia, Iron-Deficiency / pathology
-
Anemia, Macrocytic / complications
-
Anemia, Macrocytic / mortality*
-
Anemia, Macrocytic / pathology
-
Carcinoma, Renal Cell / complications
-
Carcinoma, Renal Cell / mortality
-
Carcinoma, Renal Cell / pathology
-
Castleman Disease / complications
-
Castleman Disease / mortality
-
Castleman Disease / pathology
-
Female
-
Hodgkin Disease / complications
-
Hodgkin Disease / mortality
-
Hodgkin Disease / pathology
-
Humans
-
Male
-
Middle Aged
-
Prevalence
-
Primary Myelofibrosis / complications
-
Primary Myelofibrosis / mortality*
-
Primary Myelofibrosis / pathology
-
Thalassemia / complications
-
Thalassemia / mortality
-
Thalassemia / pathology