Acute bacterial meningitis in a patient receiving ibuprofen

J Infect. 2005 Nov;51(4):336-7. doi: 10.1016/j.jinf.2004.06.017.

Abstract

We report an atypical presentation of meningitis due to Neisseria meningitidis in a patient who received large doses of ibuprofen. Anti-inflammatory therapy such as NSAIDs could reduce CSF inflammation and modify the clinical outcome in patients with bacterial meningitis. However, the use of NSAIDs is not recommended in bacterial meningitis due to a lack of studies.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Amoxicillin / therapeutic use
  • Anti-Bacterial Agents / therapeutic use
  • Anti-Inflammatory Agents, Non-Steroidal / adverse effects*
  • Contraindications
  • Humans
  • Ibuprofen / adverse effects*
  • Lymphocytosis / etiology
  • Male
  • Meningitis, Meningococcal / cerebrospinal fluid
  • Meningitis, Meningococcal / chemically induced*
  • Meningitis, Meningococcal / drug therapy
  • Meningitis, Meningococcal / microbiology
  • Neisseria meningitidis / isolation & purification

Substances

  • Anti-Bacterial Agents
  • Anti-Inflammatory Agents, Non-Steroidal
  • Amoxicillin
  • Ibuprofen