IgH/TCR rearrangements are common in MLL translocated adult AML and suggest an early T/myeloid or B/myeloid maturation arrest, which correlates with the MLL partner

Leukemia. 2005 Dec;19(12):2337-8. doi: 10.1038/sj.leu.2403981.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Adult
  • B-Lymphocytes / pathology
  • Cell Lineage*
  • Gene Rearrangement
  • Genes, T-Cell Receptor
  • Humans
  • Immunoglobulin Heavy Chains / genetics
  • Leukemia, Myeloid / genetics
  • Leukemia, Myeloid / pathology*
  • Myeloid Cells / pathology
  • Myeloid-Lymphoid Leukemia Protein / genetics*
  • T-Lymphocytes / pathology
  • Translocation, Genetic*

Substances

  • Immunoglobulin Heavy Chains
  • Myeloid-Lymphoid Leukemia Protein