Mechanisms of resistance to beta-lactams in some common Gram-negative bacteria causing nosocomial infections

Carlos José Suárez; Karen Lolans; Maria Virginia Villegas; John P Quinn

doi:10.1586/14787210.3.6.915

Mechanisms of resistance to beta-lactams in some common Gram-negative bacteria causing nosocomial infections

Expert Rev Anti Infect Ther. 2005 Dec;3(6):915-22. doi: 10.1586/14787210.3.6.915.

Authors

Carlos José Suárez¹, Karen Lolans, Maria Virginia Villegas, John P Quinn

Affiliation

¹ Bacterial Resistance Line, CIDEIM (International Center for Medical Research and Training), Cali, Colombia. [email protected]

PMID: 16307504
DOI: 10.1586/14787210.3.6.915

Abstract

Gram-negative bacilli remain major killers of hospitalized patients and continue to evolve new resistance mechanisms. This review describes the mechanisms of resistance to beta-lactam antibiotics from those Gram-negative pathogens most often isolated from nosocomial infections.

Publication types

Review

MeSH terms

Animals
Anti-Bacterial Agents / pharmacology
Anti-Bacterial Agents / therapeutic use
Cross Infection / drug therapy*
Cross Infection / genetics
Gram-Negative Bacteria / drug effects
Gram-Negative Bacteria / genetics
Gram-Negative Bacterial Infections / drug therapy*
Gram-Negative Bacterial Infections / microbiology
Humans
beta-Lactam Resistance / drug effects
beta-Lactam Resistance / genetics*
beta-Lactams / pharmacology
beta-Lactams / therapeutic use*

Substances

Anti-Bacterial Agents
beta-Lactams