[Detection of human metapneumovirus in children hospitalized for acute lower respiratory infection in Santiago, Chile]

Rev Med Chil. 2005 Sep;133(9):1059-64. doi: 10.4067/s0034-98872005000900009. Epub 2005 Nov 9.
[Article in Spanish]

Abstract

Background: Human metapneumovirus (hMPV) has recently been described as a new causal agent of acute low respiratory infection (ALRI) in children. In South America, detection has been reported only in Brazil and Argentina.

Aim: To detect hMPV in children hospitalized for ALRI in Santiago, Chile.

Material and methods: Reverse transcription-polymerase chain reaction (RT-PCR) was used to detect N gene of hMPV in 182 nasopharyngeal aspirates that were negative for common respiratory viruses, obtained from children hospitalized for ALRI during 2003.

Results: Ten samples (5.4%) were positive, most of them detected during spring months.

Conclusions: Since hMPV was detected among infants with ALRI in Santiago, further studies on their prevalence should be done in South America.

Publication types

  • English Abstract

MeSH terms

  • Acute Disease
  • Chile / epidemiology
  • Electrophoresis, Agar Gel
  • Hospitalization
  • Humans
  • Infant
  • Infant, Newborn
  • Metapneumovirus / isolation & purification*
  • Nasopharynx / virology
  • Paramyxoviridae Infections / complications*
  • Paramyxoviridae Infections / diagnosis
  • Paramyxoviridae Infections / epidemiology
  • Respiratory Syncytial Virus Infections / complications
  • Respiratory Syncytial Virus Infections / diagnosis
  • Respiratory Syncytial Virus Infections / epidemiology
  • Respiratory Tract Infections / epidemiology
  • Respiratory Tract Infections / virology*
  • Reverse Transcriptase Polymerase Chain Reaction