Resuscitation from adrenaline resistant electro-mechanical dissociation facilitated by levosimendan in a young man with idiopathic dilated cardiomyopathy

Resuscitation. 2006 Jan;68(1):147-9. doi: 10.1016/j.resuscitation.2005.06.007. Epub 2005 Dec 1.

Abstract

A 32-year-old man with severe congestive heart failure due to idiopathic cardiomyopathy developed ventricular tachycardia followed by electro-mechanical dissociation. High doses of conventional inotropic medications failed to restore haemodynamics. The additional infusion of levosimendan in conjunction with external chest compressions for 2.5 h restored haemodynamics, followed by complete recovery, including normal neurological function. The anti-stunning properties of levosimendan probably attenuated post-ischaemic myocardial dysfunction and helped to restore normal cardiac output.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cardiomyopathy, Dilated / complications*
  • Cardiopulmonary Resuscitation*
  • Cardiotonic Agents / therapeutic use*
  • Epinephrine / therapeutic use
  • Heart Arrest / drug therapy*
  • Heart Arrest / etiology
  • Heart Failure / complications*
  • Humans
  • Hydrazones / therapeutic use*
  • Male
  • Pyridazines / therapeutic use*
  • Simendan

Substances

  • Cardiotonic Agents
  • Hydrazones
  • Pyridazines
  • Simendan
  • Epinephrine