Abstract
A survey was done to determine the prevalence of premature ovarian failure among female transplant patients. Within the 109 patients who replied, premature ovarian failure was found to be less common among women given reduced-intensity conditioning regimens (37.5%) than among those given high-dose conditioning regimens (79%) for hematopoietic stem-cell transplantation (p=0.007).
MeSH terms
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Adolescent
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Adult
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Antineoplastic Agents / administration & dosage
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Antineoplastic Agents / adverse effects*
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Female
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Follow-Up Studies
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Hematopoietic Stem Cell Transplantation*
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Humans
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Prevalence
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Primary Ovarian Insufficiency / epidemiology
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Primary Ovarian Insufficiency / etiology*
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Radiation Injuries / epidemiology
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Radiation Injuries / etiology
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Surveys and Questionnaires
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Transplantation Conditioning / adverse effects*
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Transplantation Conditioning / methods
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Transplantation, Autologous
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Transplantation, Homologous
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Whole-Body Irradiation / adverse effects