Abstract
A new transcription unit of the f1 gene cluster was found. The DNA sequencing revealed one long open reading frame. Deletion and frame shift mutation analyses have demonstrated the importance of a corresponding gene product for the F1 antigen biosynthesis. A homology of the deduced amino acid sequence with that of AraC family DNA-binding regulators was shown. A potential regulatory DNA region is discussed.
MeSH terms
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Amino Acid Sequence
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Antigens, Bacterial / genetics*
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Antigens, Bacterial / metabolism
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Bacterial Capsules / genetics*
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Bacterial Capsules / metabolism
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Bacterial Proteins / genetics*
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Bacterial Proteins / metabolism
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Base Sequence
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DNA, Bacterial
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Genes, Bacterial*
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Genes, Regulator*
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Molecular Sequence Data
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Restriction Mapping
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Sequence Alignment
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Yersinia pestis / genetics*
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Yersinia pestis / metabolism
Substances
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Antigens, Bacterial
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Bacterial Proteins
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DNA, Bacterial
Associated data
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GENBANK/S86392
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GENBANK/S90294
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GENBANK/S90296
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GENBANK/S90298
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GENBANK/X61996
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GENBANK/X65503
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GENBANK/X65504
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GENBANK/X66534
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GENBANK/Z11695
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GENBANK/Z11696