Abstract
The incidence of diagnosed xanthogranuloma of the sellar region is very low [1, 2, 5, 6]. We report about two cases 1) in a 57-year-old female and 2) in a 5-year-old boy. In both cases radiographic findings revealed an inhomogeneous, contrast enhancing sellar lesion. Histopathology showed the typical features of a xanthogranuloma of the sellar region with cholesterol clefts, lympho-plasmacellular infiltrates, marked hemosiderin deposits, multinucleated foreign body giant cells around cholesterol clefts, accumulation of macrophages and only small epithelial cell clusters [6]. As xanthogranuloma of the sellar region are rarely diagnosed we want to draw attention to this rather unusual diagnosis.
MeSH terms
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Child, Preschool
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Cholesterol / metabolism
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Craniopharyngioma / diagnosis
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Diagnosis, Differential
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Female
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Giant Cells, Foreign-Body / pathology
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Hemosiderin / metabolism
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Humans
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Hypopituitarism / etiology
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Hypopituitarism / physiopathology
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Hypopituitarism / surgery
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Lymphocytes / pathology
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Macrophages / pathology
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Male
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Middle Aged
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Neurosurgical Procedures
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Pituitary Gland / pathology*
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Pituitary Gland / physiopathology
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Pituitary Gland / surgery
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Postoperative Complications / etiology
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Postoperative Complications / physiopathology
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Postoperative Complications / therapy
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Sella Turcica / pathology*
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Sella Turcica / physiopathology
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Sella Turcica / surgery
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Skull Base Neoplasms / diagnosis*
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Skull Base Neoplasms / physiopathology*
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Skull Base Neoplasms / surgery
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Treatment Outcome
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Xanthogranuloma, Juvenile / diagnosis*
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Xanthogranuloma, Juvenile / physiopathology*
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Xanthogranuloma, Juvenile / surgery