Canine carpal joint fusion: a model for four-corner arthrodesis using a porous tantalum implant

J Hand Surg Am. 2005 Nov;30(6):1128-35. doi: 10.1016/j.jhsa.2005.08.008.

Abstract

Purpose: Interest has focused on porous materials that promote bony ingrowth. In this study a porous tantalum implant was used as an adjunct to intercarpal stabilization in a canine model of wrist arthrodesis.

Methods: A defect was created at the junction of the radiocarpal, ulnocarpal, and fourth carpal bones, analogous to a four-corner fusion site in humans. A tantalum cylinder was press-fit and stabilized with K-wires. Controls were represented by creating the defect without implant placement. Animals were killed at 4, 8, and 12 weeks.

Results: Histology showed bony ingrowth as early as 4 weeks and mechanical testing showed a statistically significant increase in strength of the construct over time. Controls failed to achieve union at any time point.

Conclusions: The implant served as an adjunct to stabilization of the carpus in this model of four-corner fusion, suggesting a novel application of this material in conditions in which bone graft has been required previously. This study represents a preliminary investigation of the use of a tantalum device for intercarpal stabilization; it does not compare this technique with conventional methods.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Arthrodesis / methods*
  • Bone Regeneration
  • Bone Wires
  • Carpal Joints / pathology
  • Carpal Joints / surgery*
  • Carpus, Animal / pathology
  • Carpus, Animal / surgery*
  • Dogs
  • Joint Instability / surgery
  • Materials Testing
  • Microscopy
  • Models, Animal
  • Porosity
  • Prostheses and Implants*
  • Tantalum

Substances

  • Tantalum