Total synthesis and biological assessment of benzimidazole-based analogues of epothilone A: ambivalent effects on cancer cell growth inhibition

Chembiochem. 2006 Jan;7(1):54-7. doi: 10.1002/cbic.200500351.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Benzimidazoles / chemistry*
  • Cell Line, Tumor
  • Cell Proliferation / drug effects
  • Drug Screening Assays, Antitumor
  • Epothilones / chemical synthesis*
  • Epothilones / chemistry
  • Epothilones / pharmacology*
  • Humans
  • Molecular Conformation
  • Stereoisomerism
  • Structure-Activity Relationship

Substances

  • Benzimidazoles
  • Epothilones
  • epothilone A
  • benzimidazole