Abstract
A 56-year-old man developed a highly aggressive squamous cell carcinoma (SCC) on the upper back five years ago renal transplantation and subsequent immunosuppression. The tumor was excised using the three-dimensional micrographic technique; after the formation of granulation tissue, the wound was covered with a Meshgraft. His cyclosporine A dose was reduced from 2.5 to 2.0 mg/kg. The patient was counseled on sun avoidance and use of sunscreens, as well as placed on low-dose oral acitretin and imiquimod 5% cream to control actinic keratoses. He is followed every 3 months by a dermatologist and has shown no evidence of recurrence over 2 years.
MeSH terms
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Acitretin / administration & dosage
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Acitretin / therapeutic use
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Adjuvants, Immunologic / administration & dosage
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Adjuvants, Immunologic / therapeutic use
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Administration, Oral
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Aminoquinolines / administration & dosage
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Aminoquinolines / therapeutic use
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Antineoplastic Agents / administration & dosage
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Antineoplastic Agents / therapeutic use
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Carcinoma, Squamous Cell / etiology*
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Carcinoma, Squamous Cell / pathology
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Carcinoma, Squamous Cell / prevention & control
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Carcinoma, Squamous Cell / surgery
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Counseling
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Cyclosporine / administration & dosage*
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Follow-Up Studies
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Humans
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Imiquimod
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Immunocompromised Host*
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Immunosuppressive Agents / administration & dosage*
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Keratolytic Agents / administration & dosage
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Keratolytic Agents / therapeutic use
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Keratosis / drug therapy
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Keratosis / prevention & control
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Kidney Transplantation*
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Male
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Middle Aged
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Ointments
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Skin / pathology
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Skin Neoplasms / etiology*
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Skin Neoplasms / pathology
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Skin Neoplasms / prevention & control
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Skin Neoplasms / surgery
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Sunscreening Agents / administration & dosage
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Time Factors
Substances
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Adjuvants, Immunologic
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Aminoquinolines
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Antineoplastic Agents
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Immunosuppressive Agents
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Keratolytic Agents
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Ointments
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Sunscreening Agents
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Cyclosporine
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Acitretin
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Imiquimod