A new lavandulylated flavonoid with free radical and ONOO- scavenging activities from Sophora flavescens

Arch Pharm Res. 2005 Dec;28(12):1333-6. doi: 10.1007/BF02977897.

Abstract

A new lavandulylated flavonoid, 8-lavandulylkaempferol (1), was isolated from the roots of Sophora flavescens AITON (Leguminosae). The structure of this compound was determined via spectroscopic analysis. Compound 1 was determined to be a scavenger on both 1,1-diphenyl-2-picrylhydrazyl radicals and ONOO-.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biphenyl Compounds / antagonists & inhibitors
  • Biphenyl Compounds / metabolism
  • Drugs, Chinese Herbal / chemistry
  • Drugs, Chinese Herbal / pharmacology
  • Flavonoids / chemistry
  • Flavonoids / isolation & purification*
  • Flavonoids / pharmacology
  • Free Radical Scavengers / chemistry
  • Free Radical Scavengers / isolation & purification*
  • Free Radical Scavengers / pharmacology
  • Hydrazines / antagonists & inhibitors
  • Hydrazines / metabolism
  • Kaempferols / chemistry
  • Kaempferols / isolation & purification*
  • Kaempferols / pharmacology*
  • Molecular Structure
  • Peroxynitrous Acid / antagonists & inhibitors
  • Peroxynitrous Acid / metabolism
  • Picrates
  • Plant Extracts / chemistry
  • Plant Extracts / isolation & purification
  • Plant Extracts / pharmacology
  • Plant Roots / chemistry
  • Plants, Medicinal / chemistry
  • Solvents / chemistry
  • Sophora*
  • Spectroscopy, Fourier Transform Infrared / methods

Substances

  • 8-lavandulylkaempferol
  • Biphenyl Compounds
  • Drugs, Chinese Herbal
  • Flavonoids
  • Free Radical Scavengers
  • Hydrazines
  • Kaempferols
  • Picrates
  • Plant Extracts
  • Solvents
  • Peroxynitrous Acid
  • kaempferol
  • 1,1-diphenyl-2-picrylhydrazyl