[A 65-year-old man with liver metastases after lung cancer resection that responded to concomitant use of gemcitabine and carboplatin]

Gan To Kagaku Ryoho. 2006 Jan;33(1):69-71. doi: 10.2217/14750708.3.1.69.
[Article in Japanese]

Abstract

A 65-year-old male with liver metastases after lung cancer resection was treated with five courses of chemotherapy consisting of gemcitabine (GEM) 1,000 mg/m2 (day 1, 8, every 4 weeks) plus carboplatin (CBDCA) AUC 6 (day 1, every 4 weeks). A partial response (PR) was achieved, his symptoms abated and his quality of life(QOL) improved. Although bone marrow suppression was observed as a side effect, it was within the tolerable range and did not interfere with therapy. This approach may be worth considering as a first-line anti-cancer chemotherapy for recurrence lung cancer.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Carboplatin / administration & dosage
  • Carcinoma, Small Cell / drug therapy
  • Carcinoma, Small Cell / secondary*
  • Deoxycytidine / administration & dosage
  • Deoxycytidine / analogs & derivatives
  • Drug Administration Schedule
  • Gemcitabine
  • Humans
  • Liver Neoplasms / drug therapy*
  • Liver Neoplasms / secondary*
  • Lung Neoplasms / pathology*
  • Lung Neoplasms / surgery
  • Lymph Node Excision
  • Male
  • Pneumonectomy*
  • Postoperative Period
  • Quality of Life

Substances

  • Deoxycytidine
  • Carboplatin
  • Gemcitabine