Dual infection with Mycobacterium tuberculosis and Pneumocystis jiroveci Lymphadenitis in a Patient with HIV infection: case report and review of the literature

Thana Khawcharoenporn; Anucha Apisarnthanarak; Dussadee Sakonlaya; Linda M Mundy; Thomas C Bailey

doi:10.1089/apc.2006.20.1

Dual infection with Mycobacterium tuberculosis and Pneumocystis jiroveci Lymphadenitis in a Patient with HIV infection: case report and review of the literature

AIDS Patient Care STDS. 2006 Jan;20(1):1-5. doi: 10.1089/apc.2006.20.1.

Authors

Thana Khawcharoenporn¹, Anucha Apisarnthanarak, Dussadee Sakonlaya, Linda M Mundy, Thomas C Bailey

Affiliation

¹ Department of Medicine, Thammasart University Hospital, Pratumthani, Thailand.

PMID: 16426150
DOI: 10.1089/apc.2006.20.1

Abstract

We report a case of dual Mycobacterium tuberculosis (TB) and Pneumocystis jiroveci (carinii) (PCP) lymphadenitis in a patient with HIV who had been receiving trimethoprim-sulfamethoxazole (TMP-SMX) as systemic prophylaxis for PCP. This patient was successfully treated with antituberculosis medications and TMP-SMX. Our review of the literature identified this as the first reported case of dual TB and PCP lymphadenitis in an HIV-infected host and highlights the potential limitations of TMP-SMX prophylaxis.

Publication types

Case Reports
Review

MeSH terms

Adult
Antibiotic Prophylaxis
Female
HIV Infections / complications*
Humans
Lymphadenitis / complications*
Lymphadenitis / microbiology
Mycobacterium tuberculosis*
Pneumocystis Infections / complications*
Pneumocystis Infections / microbiology
Pneumocystis carinii*
Pneumonia, Pneumocystis / prevention & control
Trimethoprim, Sulfamethoxazole Drug Combination / therapeutic use
Tuberculosis, Lymph Node / complications*
Tuberculosis, Lymph Node / microbiology

Substances

Trimethoprim, Sulfamethoxazole Drug Combination