Clearance of enteric Salmonella enterica serovar Typhimurium in chickens is independent of B-cell function

Infect Immun. 2006 Feb;74(2):1442-4. doi: 10.1128/IAI.74.2.1442-1444.2006.

Abstract

Salmonella enterica serovar Typhimurium colonizes the gut of chickens and is cleared from the intestine within about 3 weeks. Infection induces high levels of specific antibody, but B cells do not play an essential role in clearance of primary infection or in the enhanced clearance after secondary challenge.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antibodies, Bacterial / blood
  • B-Lymphocytes / physiology*
  • Chickens / immunology*
  • Poultry Diseases / immunology*
  • Poultry Diseases / microbiology
  • Salmonella Infections, Animal / immunology*
  • Salmonella Infections, Animal / microbiology
  • Salmonella typhimurium / immunology
  • Salmonella typhimurium / pathogenicity*

Substances

  • Antibodies, Bacterial