The effect of glatiramer acetate treatment on pre-existing headaches in patients with MS

Neurology. 2006 Jan 24;66(2):275-7. doi: 10.1212/01.wnl.0000194317.75449.91.

Abstract

During the first 6 months of glatiramer acetate therapy in 82 consecutive patients with multiple sclerosis, in only 6% frequency of pre-existing headaches increased by more than 50%. This is less than the headache aggravation reported in an earlier study in up to 35% of patients during the first 6 months on interferon beta.

Publication types

  • Controlled Clinical Trial

MeSH terms

  • Adjuvants, Immunologic / therapeutic use
  • Adult
  • Female
  • Glatiramer Acetate
  • Headache / epidemiology*
  • Headache / etiology*
  • Humans
  • Immunosuppressive Agents / adverse effects
  • Immunosuppressive Agents / therapeutic use*
  • Incidence
  • Interferon-beta / therapeutic use
  • Male
  • Middle Aged
  • Multiple Sclerosis / complications*
  • Multiple Sclerosis / drug therapy*
  • Peptides / adverse effects
  • Peptides / therapeutic use*
  • Time Factors

Substances

  • Adjuvants, Immunologic
  • Immunosuppressive Agents
  • Peptides
  • Glatiramer Acetate
  • Interferon-beta