Two adult anticoagulated patients after valve replacement were scheduled for inguinal herniorrhaphy. For inguinal herniorrhaphy in adults, spinal anesthesia is a common anesthetic method. In order to avoid spinal hematoma due to spinal anesthesia, however, we employed general anesthesia combined with ilioinguinal nerve block. Following induction of anesthesia, a laryngeal mask airway was inserted. Ilioinguinal nerve block was performed with 0.25% bupivacaine 20ml. Ilioinguinal nerve block was effective for maintaining hemodynamic stability throughout the operation, and decreased postoperative pain. This technique appears to be a simple and safe method for providing effective and long-lasting perioperative analgesia following inguinal herniorrhaphy in adult patients.