Multilocus genotyping of Cryptosporidium sp. isolates from human immunodeficiency virus-infected individuals in South India

J Clin Microbiol. 2006 Feb;44(2):632-4. doi: 10.1128/JCM.44.2.632-634.2006.

Abstract

This study characterized cryptosporidial infections in 48 human immunodeficiency virus-infected individuals in India by multilocus genotyping. Cryptosporidium hominis, C. parvum, C. felis, C. muris, and C. meleagridis were identified. Cpgp40/15 PCR-restriction fragment length polymorphism identified six subgenotypes. Cryptosporidial diarrhea was associated with decreased CD4 counts, below 200 (P = 0.009), but not high viral loads.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • AIDS-Related Opportunistic Infections / parasitology*
  • Adult
  • Animals
  • Cryptosporidiosis / parasitology*
  • Cryptosporidium / classification*
  • Cryptosporidium / genetics
  • Cryptosporidium / isolation & purification
  • DNA, Protozoan / analysis
  • Genotype
  • HIV Infections / complications*
  • Humans
  • India
  • Molecular Sequence Data
  • Polymerase Chain Reaction
  • Polymorphism, Restriction Fragment Length
  • Protozoan Proteins / genetics
  • Sequence Analysis, DNA

Substances

  • Cpgp40-15 protein, Cryptosporidium parvum
  • DNA, Protozoan
  • Protozoan Proteins

Associated data

  • GENBANK/DQ067564
  • GENBANK/DQ067565
  • GENBANK/DQ067566
  • GENBANK/DQ067567
  • GENBANK/DQ067568
  • GENBANK/DQ067569
  • GENBANK/DQ067570