Platelet interactions with vessel wall components during thrombogenesis

Zaverio M Ruggeri

doi:10.1016/j.bcmd.2005.12.012

Platelet interactions with vessel wall components during thrombogenesis

Blood Cells Mol Dis. 2006 Mar-Apr;36(2):145-7. doi: 10.1016/j.bcmd.2005.12.012. Epub 2006 Feb 15.

Author

Zaverio M Ruggeri¹

Affiliation

¹ Roon Center for Arteriosclerosis and Thrombosis, Division of Experimental Hemostasis and Thrombosis, Department of Molecular and Experimental Medicine, The Scripps Research Institute-MEM 175, La Jolla, CA 92037, USA. [email protected]

PMID: 16469513
DOI: 10.1016/j.bcmd.2005.12.012

Abstract

We discuss the interrelationships of platelet glycoprotein receptors, von Willebrand factor, collagen, non-collagen matrix protein, and vascular cells in the complex events of platelet plug and subsequent thrombus formation.

Publication types

Review

MeSH terms

Animals
Endothelium, Vascular / pathology*
Extracellular Matrix Proteins
Humans
Platelet Adhesiveness*
Receptors, Cell Surface
Thrombosis / etiology*
Thrombosis / pathology
von Willebrand Factor

Substances

Extracellular Matrix Proteins
Receptors, Cell Surface
von Willebrand Factor