[Late effects after chemotherapy]

Internist (Berl). 2006 Mar;47(3):266-8, 270-72. doi: 10.1007/s00108-006-1577-z.
[Article in German]

Abstract

Today, about 60% of adult patients and 80% children diagnosed with cancer will survive 5 years after diagnosis. Approximately two thirds of cancer survivors will experience at least one late effect, and about one third severe or life threatening late effects. The aim of cancer treatment today is to cure the malignant disease but at the same time, to minimize the incidence of post-treatment complications. In the current overview we summarize, based on the most recent publications, typical late effects in cancer survivors.

MeSH terms

  • Adult
  • Antineoplastic Agents / adverse effects*
  • Antineoplastic Agents / therapeutic use
  • Antineoplastic Combined Chemotherapy Protocols / adverse effects
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Cardiomyopathies / chemically induced
  • Cardiomyopathies / diagnosis
  • Cardiomyopathies / therapy
  • Chemical and Drug Induced Liver Injury / diagnosis
  • Chemical and Drug Induced Liver Injury / etiology
  • Chemical and Drug Induced Liver Injury / therapy
  • Child
  • Combined Modality Therapy
  • Dose-Response Relationship, Drug
  • Humans
  • Lung Diseases, Interstitial / chemically induced
  • Lung Diseases, Interstitial / diagnosis
  • Lung Diseases, Interstitial / therapy
  • Neoplasms / drug therapy*
  • Neoplasms / mortality
  • Nephritis, Interstitial / chemically induced
  • Nephritis, Interstitial / diagnosis
  • Nephritis, Interstitial / therapy
  • Nervous System Diseases / chemically induced
  • Nervous System Diseases / diagnosis
  • Nervous System Diseases / therapy
  • Pulmonary Fibrosis / chemically induced
  • Pulmonary Fibrosis / diagnosis
  • Pulmonary Fibrosis / therapy
  • Risk Factors
  • Survival Rate

Substances

  • Antineoplastic Agents