Abstract
Fournier gangrene is a necrotizing fasciitis of the perineal and genital region, which almost exclusively affects men. The cause is a polymicrobial infection associated with superficial trauma, urological diseases and operations, as well as colorectal diseases. Diabetes mellitus, alcoholism, immunosuppression and other severe illnesses are frequent co-factors. Immediate administration of systemic broad-spectrum antibiotic therapy with coverage of both gram-positive and gram-negative bacteria combined with surgical debridement and intensive medical care can lower the high mortality rate of this condition.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Adult
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Cefotaxime / therapeutic use
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Combined Modality Therapy
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Drug Therapy, Combination
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Emergencies*
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Follow-Up Studies
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Fournier Gangrene / diagnosis*
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Fournier Gangrene / pathology
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Fournier Gangrene / surgery
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Genital Diseases, Male / diagnosis*
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Genital Diseases, Male / pathology
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Genital Diseases, Male / surgery
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Humans
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Male
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Metronidazole / therapeutic use
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Necrosis
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Penile Diseases / diagnosis*
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Penile Diseases / pathology
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Penile Diseases / surgery
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Scrotum* / pathology
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Scrotum* / surgery
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Skin / pathology
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Streptococcal Infections / diagnosis*
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Streptococcal Infections / pathology
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Streptococcal Infections / surgery
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Streptococcus pyogenes*
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Tobramycin / therapeutic use
Substances
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Metronidazole
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Cefotaxime
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Tobramycin