Efficient synthesis of C-11 functionalized steroids

Steroids. 2006 Jun;71(6):459-68. doi: 10.1016/j.steroids.2006.01.003. Epub 2006 Feb 14.

Abstract

An efficient synthesis from readily available materials of numerous steroids functionalized at C-11 position, interesting from a biological point of view, is described using our general approach. The characteristic (1)H and (13)C NMR spectroscopic features of the synthesized steroids are reported.

MeSH terms

  • Magnetic Resonance Spectroscopy
  • Molecular Conformation
  • Molecular Structure
  • Nitriles / chemistry
  • Steroids / chemical synthesis*
  • Steroids / chemistry*

Substances

  • Nitriles
  • Steroids